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A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions

The aim of this study was to develop a three-dimensional (3D) model of the human blood-brain barrier in vitro, which mimics the cellular architecture of the CNS and could be used to analyse the delivery of nanoparticles to cells of the CNS. The model includes human astrocytes set in a collagen gel,...

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Dettagli Bibliografici
Pubblicato in:F1000Res
Autori principali: Sreekanthreddy, Peddagangannagari, Gromnicova, Radka, Davies, Heather, Phillips, James, Romero, Ignacio A., Male, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000Research 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732555/
https://ncbi.nlm.nih.gov/pubmed/26870320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7142.2
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