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A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions

The aim of this study was to develop a three-dimensional (3D) model of the human blood-brain barrier in vitro, which mimics the cellular architecture of the CNS and could be used to analyse the delivery of nanoparticles to cells of the CNS. The model includes human astrocytes set in a collagen gel,...

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Détails bibliographiques
Publié dans:F1000Res
Auteurs principaux: Sreekanthreddy, Peddagangannagari, Gromnicova, Radka, Davies, Heather, Phillips, James, Romero, Ignacio A., Male, David
Format: Artigo
Langue:Inglês
Publié: F1000Research 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732555/
https://ncbi.nlm.nih.gov/pubmed/26870320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7142.2
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