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Transcriptional Control of the Multi-Drug Transporter ABCB1 by Transcription Factor Sp3 in Different Human Tissues

The ATP-binding cassette (ABC) transporter ABCB1, encoded by the multidrug resistance gene MDR1, is expressed on brain microvascular endothelium and several types of epithelium, but not on endothelia outside the CNS. It is an essential component of the blood-brain barrier. The aim of this study was...

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Detalhes bibliográficos
Main Authors: Gromnicova, Radka, Romero, Ignacio, Male, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485001/
https://ncbi.nlm.nih.gov/pubmed/23133566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048189
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