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Gold nanocarriers for transport of oligonucleotides across brain endothelial cells

Treatment of diseases that affect the CNS by gene therapy requires delivery of oligonucleotides to target cells within the brain. As the blood brain barrier prevents movement of large biomolecules, current approaches involve direct injection of the oligonucleotides, which is invasive and may have on...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Fatima, Nayab, Gromnicova, Radka, Loughlin, Jane, Sharrack, Basil, Male, David
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498062/
https://ncbi.nlm.nih.gov/pubmed/32941446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236611
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