Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer

Molecular differences in tumor locations may contribute to the sidedness-specific response to cetuximab in metastatic colorectal cancer (mCRC). We investigated genes associated with the response to cetuximab treatment depending on tumor sidedness. Our study included 77 patients with mCRC (13/63, rig...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Sunakawa, Yu, Mogushi, Kaoru, Lenz, Heinz-Josef, Zhang, Wu, Tsuji, Akihito, Takahashi, Takehiro, Denda, Tadamichi, Shimada, Ken, Kochi, Mitsugu, Nakamura, Masato, Kotaka, Masahito, Segawa, Yoshihiko, Tanioka, Hiroaki, Negoro, Yuji, Moran, Miriana, Astrow, Stephanie H., Hsiang, Jack, Stephens, Craig, Fujii, Masashi, Ichikawa, Wataru
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497846/
https://ncbi.nlm.nih.gov/pubmed/30275242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0694
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