Combined assessment of EGFR-related molecules to predict outcome of 1st-line cetuximab-containing chemotherapy for metastatic colorectal cancer

Several studies have reported that epidermal growth factor receptor (EGFR)-related molecules may serve as predictors of cetuximab treatment for metastatic colorectal cancer (mCRC), such as EGFR gene copy number (GCN), expression of 2 ligands of EGFR, amphiregulin (AREG) and epiregulin (EREG), and EG...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Sunakawa, Yu, Yang, Dongyun, Moran, Miriana, Astrow, Stephanie H., Tsuji, Akihito, Stephens, Craig, Zhang, Wu, Cao, Shu, Takahashi, Takehiro, Denda, Tadamichi, Shimada, Ken, Kochi, Mitsugu, Nakamura, Masato, Kotaka, Masahito, Segawa, Yoshihiko, Masuishi, Toshiki, Takeuchi, Masahiro, Fujii, Masashi, Nakajima, Toshifusa, Ichikawa, Wataru, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970538/
https://ncbi.nlm.nih.gov/pubmed/27104867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1178426
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