Combined assessment of EGFR-related molecules to predict outcome of 1st-line cetuximab-containing chemotherapy for metastatic colorectal cancer

Several studies have reported that epidermal growth factor receptor (EGFR)-related molecules may serve as predictors of cetuximab treatment for metastatic colorectal cancer (mCRC), such as EGFR gene copy number (GCN), expression of 2 ligands of EGFR, amphiregulin (AREG) and epiregulin (EREG), and EG...

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Vydáno v:Cancer Biol Ther
Hlavní autoři: Sunakawa, Yu, Yang, Dongyun, Moran, Miriana, Astrow, Stephanie H., Tsuji, Akihito, Stephens, Craig, Zhang, Wu, Cao, Shu, Takahashi, Takehiro, Denda, Tadamichi, Shimada, Ken, Kochi, Mitsugu, Nakamura, Masato, Kotaka, Masahito, Segawa, Yoshihiko, Masuishi, Toshiki, Takeuchi, Masahiro, Fujii, Masashi, Nakajima, Toshifusa, Ichikawa, Wataru, Lenz, Heinz-Josef
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970538/
https://ncbi.nlm.nih.gov/pubmed/27104867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1178426
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