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Cetuximab in the management of colorectal cancer

Cetuximab, a chimeric IgG1 monoclonal antibody that targets the ligand-binding domain of the epidermal growth factor receptor (EGFR), is active in metastatic colorectal cancer (mCRC). As an IgG1 antibody, cetuximab may exert its antitumor efficacy through both EGFR antagonism and antibody-dependent...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Lenz, Heinz-Josef
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721306/
https://ncbi.nlm.nih.gov/pubmed/19707318
Tagiau: Ychwanegu Tag
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