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Cetuximab in the management of colorectal cancer

Cetuximab, a chimeric IgG1 monoclonal antibody that targets the ligand-binding domain of the epidermal growth factor receptor (EGFR), is active in metastatic colorectal cancer (mCRC). As an IgG1 antibody, cetuximab may exert its antitumor efficacy through both EGFR antagonism and antibody-dependent...

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Bibliografski detalji
Glavni autor: Lenz, Heinz-Josef
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721306/
https://ncbi.nlm.nih.gov/pubmed/19707318
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