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Evaluation of Pharmacokinetics and Dose Proportionality of Diazepam After Intranasal Administration of NRL‐1 to Healthy Volunteers

NRL‐1 is a novel intranasal formulation of diazepam that is being evaluated as rescue medication in patients with epilepsy who experience bouts of increased seizure activity despite stable regimens of antiepileptic drugs. This phase 1, open‐label, randomized, crossover study in healthy adult volunte...

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Pubblicato in:Clin Pharmacol Drug Dev
Autori principali: Tanimoto, Sarina, Pesco Koplowitz, Luana, Lowenthal, Richard E., Koplowitz, Barry, Rabinowicz, Adrian L., Carrazana, Enrique
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497078/
https://ncbi.nlm.nih.gov/pubmed/31916704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.767
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