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Pharmacokinetics and safety of VALTOCO (NRL‐1; diazepam nasal spray) in patients with epilepsy during seizure (ictal/peri‐ictal) and nonseizure (interictal) conditions: A phase 1, open‐label study

OBJECTIVE: To assess pharmacokinetics and safety of diazepam nasal spray (NRL‐1; VALTOCO®) in pediatric and adult patients with epilepsy in seizure and nonseizure states. METHODS: A single dose of diazepam nasal spray (5, 10, 15, or 20 mg based on weight) was administered during each of two conditio...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Hogan, Robert Edward, Tarquinio, Daniel, Sperling, Michael R., Klein, Pavel, Miller, Ian, Segal, Eric B., Rabinowicz, Adrian L., Carrazana, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7383779/
https://ncbi.nlm.nih.gov/pubmed/32338380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.16506
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