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Evaluation of Pharmacokinetics and Dose Proportionality of Diazepam After Intranasal Administration of NRL‐1 to Healthy Volunteers

NRL‐1 is a novel intranasal formulation of diazepam that is being evaluated as rescue medication in patients with epilepsy who experience bouts of increased seizure activity despite stable regimens of antiepileptic drugs. This phase 1, open‐label, randomized, crossover study in healthy adult volunte...

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Vydáno v:Clin Pharmacol Drug Dev
Hlavní autoři: Tanimoto, Sarina, Pesco Koplowitz, Luana, Lowenthal, Richard E., Koplowitz, Barry, Rabinowicz, Adrian L., Carrazana, Enrique
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497078/
https://ncbi.nlm.nih.gov/pubmed/31916704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.767
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