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Reduced iron export associated with hepcidin resistance can explain the iron overload spectrum in ferroportin disease
BACKGROUND & AIMS: Ferroportin disease (FD) and hemochromatosis type 4 (HH4) are associated with variants in the ferroportin‐encoding gene SLC40A1. Both phenotypes are characterized by iron overload despite being caused by distinct variants that either mediate reduced cellular iron export in FD...
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| Publicado no: | Liver Int |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7496278/ https://ncbi.nlm.nih.gov/pubmed/32450003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14539 |
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