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A Hyperactive Kunjin Virus NS3 Helicase Mutant Demonstrates Increased Dissemination and Mortality in Mosquitoes

The unwinding of double-stranded RNA intermediates is critical for the replication and packaging of flavivirus RNA genomes. This unwinding activity is achieved by the ATP-dependent nonstructural protein 3 (NS3) helicase. In previous studies, we investigated the mechanism of energy transduction betwe...

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Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Du Pont, Kelly E., Sexton, Nicole R., McCullagh, Martin, Ebel, Gregory D., Geiss, Brian J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495370/
https://ncbi.nlm.nih.gov/pubmed/32699093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01021-20
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