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Allostery in the dengue virus NS3 helicase: Insights into the NTPase cycle from molecular simulations
The C-terminus domain of non-structural 3 (NS3) protein of the Flaviviridae viruses (e.g. HCV, dengue, West Nile, Zika) is a nucleotide triphosphatase (NTPase) -dependent superfamily 2 (SF2) helicase that unwinds double-stranded RNA while translocating along the nucleic polymer. Due to these functio...
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| 發表在: | PLoS Comput Biol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919694/ https://ncbi.nlm.nih.gov/pubmed/29659571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006103 |
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