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Allostery in the dengue virus NS3 helicase: Insights into the NTPase cycle from molecular simulations
The C-terminus domain of non-structural 3 (NS3) protein of the Flaviviridae viruses (e.g. HCV, dengue, West Nile, Zika) is a nucleotide triphosphatase (NTPase) -dependent superfamily 2 (SF2) helicase that unwinds double-stranded RNA while translocating along the nucleic polymer. Due to these functio...
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| Publicat a: | PLoS Comput Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919694/ https://ncbi.nlm.nih.gov/pubmed/29659571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006103 |
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