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Role of succinate dehydrogenase deficiency and oncometabolites in gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At the molecular level, GISTs can be categorized into two groups based on the causative oncogenic mutations. Approximately 85% of GISTs are caused by gain-of-function mutations in the tyrosi...

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Bibliografske podrobnosti
izdano v:World J Gastroenterol
Main Authors: Zhao, Yue, Feng, Fei, Guo, Qing-Hong, Wang, Yu-Ping, Zhao, Rui
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495036/
https://ncbi.nlm.nih.gov/pubmed/32982110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v26.i34.5074
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