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Role of succinate dehydrogenase deficiency and oncometabolites in gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At the molecular level, GISTs can be categorized into two groups based on the causative oncogenic mutations. Approximately 85% of GISTs are caused by gain-of-function mutations in the tyrosi...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Zhao, Yue, Feng, Fei, Guo, Qing-Hong, Wang, Yu-Ping, Zhao, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495036/
https://ncbi.nlm.nih.gov/pubmed/32982110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v26.i34.5074
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