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Role of succinate dehydrogenase deficiency and oncometabolites in gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At the molecular level, GISTs can be categorized into two groups based on the causative oncogenic mutations. Approximately 85% of GISTs are caused by gain-of-function mutations in the tyrosi...

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Publicado en:World J Gastroenterol
Autores principales: Zhao, Yue, Feng, Fei, Guo, Qing-Hong, Wang, Yu-Ping, Zhao, Rui
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Inc 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495036/
https://ncbi.nlm.nih.gov/pubmed/32982110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v26.i34.5074
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