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Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumors: Small Steps Toward Personalized Medicine?

Various molecular triggers define heterogeneous subsets of gastrointestinal stromal tumors (GISTs), differing in clinical behavior and drug sensitivity. KIT/PDGFRA -wild-type GISTs, including those succinate dehydrogenase (SDH)-deficient, are overall unresponsive to the tyrosine kinase inhibitors co...

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Detalhes bibliográficos
Main Authors: Gloria Ravegnini, Riccardo Ricci
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2019-04-01
Colecção:Epigenetics Insights
Acesso em linha:https://doi.org/10.1177/2516865719842534
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