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DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4
Translation efficiency varies considerably between different mRNAs, thereby impacting protein expression. Translation of the stress response master-regulator ATF4 increases upon stress, but the molecular mechanisms are not well understood. We discover here that translation factors DENR, MCTS1 and eI...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494916/ https://ncbi.nlm.nih.gov/pubmed/32938922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18452-2 |
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