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Identification of transcripts with short stuORFs as targets for DENR•MCTS1-dependent translation in human cells
The non-canonical initiation factors DENR and MCTS1 have been linked to cancer and autism. We recently showed in Drosophila that DENR and MCTS1 regulate translation re-initiation on transcripts containing upstream Open Reading Frames (uORFs) with strong Kozak sequences (stuORFs). Due to the medical...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473865/ https://ncbi.nlm.nih.gov/pubmed/28623304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03949-6 |
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