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Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread around the world, there is an urgent need for new assay formats to characterize the humoral response to infection. Here, we present an efficient, competitive serological assay that can simultaneously determine an ind...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Byrnes, James R., Zhou, Xin X., Lui, Irene, Elledge, Susanna K., Glasgow, Jeff E., Lim, Shion A., Loudermilk, Rita P., Chiu, Charles Y., Wang, Taia T., Wilson, Michael R., Leung, Kevin K., Wells, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494835/
https://ncbi.nlm.nih.gov/pubmed/32938700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00802-20
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