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Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread around the world, there is an urgent need for new assay formats to characterize the humoral response to infection. Here, we present an efficient, competitive serological assay that can simultaneously determine an ind...

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Détails bibliographiques
Publié dans:mSphere
Auteurs principaux: Byrnes, James R., Zhou, Xin X., Lui, Irene, Elledge, Susanna K., Glasgow, Jeff E., Lim, Shion A., Loudermilk, Rita P., Chiu, Charles Y., Wang, Taia T., Wilson, Michael R., Leung, Kevin K., Wells, James A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494835/
https://ncbi.nlm.nih.gov/pubmed/32938700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00802-20
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