A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding

As SARS-CoV-2 continues to spread around the world, there is an urgent need for new assay formats to characterize the humoral response to infection. Convalescent serum is being used for treatment and for isolation of patient-derived antibodies. However, currently there is not a simple means to estim...

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Publicado en:medRxiv
Main Authors: Byrnes, James R., Zhou, Xin X., Lui, Irene, Elledge, Susanna K., Glasgow, Jeff E., Lim, Shion A., Loudermilk, Rita, Chiu, Charles Y., Wilson, Michael R., Leung, Kevin K., Wells, James A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273274/
https://ncbi.nlm.nih.gov/pubmed/32511506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.27.20114652
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