Monosomic Loss of MIR15A/MIR16-1 Is a Driver of Multiple Myeloma Proliferation and Disease Progression

The most common genetic abnormality in multiple myeloma is the deletion of chromosome 13, seen in almost half of newly diagnosed patients. Unlike chronic lymphocytic leukemia, where a recurrent minimally deleted region including MIR15A/MIR16-1 has been mapped, the deletions in multiple myeloma predo...

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Bibliographische Detailangaben
Veröffentlicht in:Blood Cancer Discov
Hauptverfasser: Chesi, Marta, Stein, Caleb K., Garbitt, Victoria M., Sharik, Meaghen E., Asmann, Yan W., Bergsagel, Matteo, Riggs, Daniel L., Welsh, Seth J., Meermeier, Erin W., Kumar, Shaji K., Braggio, Esteban, Bergsagel, P. Leif
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for Cancer Research 2020
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494232/
https://ncbi.nlm.nih.gov/pubmed/32954360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.BCD-19-0068
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