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Molecular pathogenesis of multiple myeloma: basic and clinical updates

Multiple myeloma is divided into two distinct genetic subtypes based on chromosome content. Hyperdiploid myeloma is characterized by multiple trisomies of chromosomes 3, 5, 7, 9 11, 15, 19 and 21, and lacks recurrent immunoglobulin gene translocations. Non-hyperdiploid myeloma in contrast is charact...

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Hlavní autoři: Chesi, Marta, Bergsagel, P. Leif
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962846/
https://ncbi.nlm.nih.gov/pubmed/23456262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-013-1291-2
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