Monosomic Loss of MIR15A/MIR16-1 Is a Driver of Multiple Myeloma Proliferation and Disease Progression

The most common genetic abnormality in multiple myeloma is the deletion of chromosome 13, seen in almost half of newly diagnosed patients. Unlike chronic lymphocytic leukemia, where a recurrent minimally deleted region including MIR15A/MIR16-1 has been mapped, the deletions in multiple myeloma predo...

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Detalhes bibliográficos
Publicado no:Blood Cancer Discov
Main Authors: Chesi, Marta, Stein, Caleb K., Garbitt, Victoria M., Sharik, Meaghen E., Asmann, Yan W., Bergsagel, Matteo, Riggs, Daniel L., Welsh, Seth J., Meermeier, Erin W., Kumar, Shaji K., Braggio, Esteban, Bergsagel, P. Leif
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Cancer Research 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494232/
https://ncbi.nlm.nih.gov/pubmed/32954360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.BCD-19-0068
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