Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells

Although the efficacy of cancer radiotherapy (RT) can be enhanced by targeted immunotherapy, the immunosuppressive factors induced by radiation on tumor cells remain to be identified. Here, we report that CD47-mediated anti-phagocytosis is concurrently upregulated with HER2 in radioresistant breast...

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Zapisane w:
Opis bibliograficzny
Wydane w:Nat Commun
Główni autorzy: Candas-Green, Demet, Xie, Bowen, Huang, Jie, Fan, Ming, Wang, Aijun, Menaa, Cheikh, Zhang, Yanhong, Zhang, Lu, Jing, Di, Azghadi, Soheila, Zhou, Weibing, Liu, Lin, Jiang, Nian, Li, Tao, Gao, Tianyi, Sweeney, Colleen, Shen, Rulong, Lin, Tzu-yin, Pan, Chong-xian, Ozpiskin, Omer M., Woloschak, Gayle, Grdina, David J., Vaughan, Andrew T., Wang, Ji Ming, Xia, Shuli, Monjazeb, Arta M., Murphy, William J., Sun, Lun-Quan, Chen, Hong-Wu, Lam, Kit S., Weichselbaum, Ralph R., Li, Jian Jian
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group UK 2020
Hasła przedmiotowe:
Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490264/
https://ncbi.nlm.nih.gov/pubmed/32929084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18245-7
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