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CyclinB1/Cdk1 phosphorylates mitochondrial antioxidant MnSOD in cell adaptive response to radiation stress

Manganese superoxide dismutase (MnSOD), a major antioxidant enzyme within the mitochondria, is responsible for the detoxification of free radicals generated by cellular metabolism and environmental/therapeutic irradiation. Cell cycle-dependent kinase Cdk1, along with its regulatory partner CyclinB1,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Candas, Demet, Fan, Ming, Nantajit, Danupon, Vaughan, Andrew T., Murley, Jeffrey S., Woloschak, Gayle E., Grdina, David J., Li, Jian Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656610/
https://ncbi.nlm.nih.gov/pubmed/23243068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjs062
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