CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection

Mammalian cells are able to sense environmental oxidative and genotoxic conditions such as the environmental low dose ionizing radiation (LDIR) present naturally on earth surface. The stressed cells then can induce a so-called radioadaptive response with an enhanced cellular homeostasis and repair c...

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Veröffentlicht in:Free Radic Biol Med
Hauptverfasser: Jin, Cuihong, Qin, Lili, Shi, Yan, Candas, Demet, Fan, Ming, Lu, Chung-Ling, Vaughan, Andrew T. M., Shen, Rulong, Wu, Larry S., Liu, Rui, Li, Robert F., Murley, Jeffrey S., Gayle, Woloschak, Grdina, David J., Li, Jian Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359946/
https://ncbi.nlm.nih.gov/pubmed/25578653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.12.026
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