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Cyclin B1/Cdk1 Phosphorylation of Mitochondrial p53 Induces Anti-Apoptotic Response

The pro-apoptotic function of p53 has been well defined in preventing genomic instability and cell transformation. However, the intriguing fact that p53 contributes to a pro-survival advantage of tumor cells under DNA damage conditions raises a critical question in radiation therapy for the 50% huma...

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Bibliografiske detaljer
Main Authors: Nantajit, Danupon, Fan, Ming, Duru, Nadire, Wen, Yunfei, Reed, John C., Li, Jian Jian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925892/
https://ncbi.nlm.nih.gov/pubmed/20808790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012341
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