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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx
BACKGROUND: Population structure among study subjects may confound genetic association studies, and lack of proper correction can lead to spurious findings. The Genotype-Tissue Expression (GTEx) project largely contains individuals of European ancestry, but the v8 release also includes up to 15% of...
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| Vydáno v: | Genome Biol |
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| Hlavní autoři: | , , , , , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7488497/ https://ncbi.nlm.nih.gov/pubmed/32912333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02113-0 |
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