Bcl6 and Blimp1 reciprocally regulate ST2(+) Treg–cell development in the context of allergic airway inflammation

BACKGROUND: Bcl6 is required for the development of T follicular helper cells and T follicular regulatory (Tfr) cells that regulate germinal center responses. Bcl6 also affects the function of regulatory T (Treg) cells. OBJECTIVE: The goal of this study was to define the functions of Bcl6 in Treg ce...

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Publicado no:J Allergy Clin Immunol
Main Authors: Koh, Byunghee, Ulrich, Benjamin J., Nelson, Andrew S., Panangipalli, Gayathri, Kharwadkar, Rakshin, Wu, Wenting, Xie, Markus M., Fu, Yongyao, Turner, Matthew J., Paczesny, Sophie, Janga, Sarath Chandra, Dent, Alexander L., Kaplan, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487006/
https://ncbi.nlm.nih.gov/pubmed/32179158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.03.002
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