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A conserved enhancer regulates Il9 expression in multiple lineages

Cytokine genes are regulated by multiple regulatory elements that confer tissue-specific and activation-dependent expression. The cis-regulatory elements of the gene encoding IL-9, a cytokine that promotes allergy, autoimmune inflammation and tumor immunity, have not been defined. Here we identify a...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Koh, Byunghee, Abdul Qayum, Amina, Srivastava, Rajneesh, Fu, Yongyao, Ulrich, Benjamin J., Janga, Sarath Chandra, Kaplan, Mark H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237898/
https://ncbi.nlm.nih.gov/pubmed/30442929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07202-0
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