STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus

T helper cell differentiation requires lineage-defining transcription factors and factors that have shared expression among multiple subsets. BATF is required for development of multiple Th subsets but functions in a lineage-specific manner. BATF is required for IL-9 production in Th9 cells but in c...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Fu, Yongyao, Wang, Jocelyn, Panangipalli, Gayathri, Ulrich, Benjamin J., Koh, Byunghee, Xu, Chengxian, Kharwadkar, Rakshin, Chu, Xiaona, Wang, Yue, Gao, Hongyu, Wu, Wenting, Sun, Jie, Tepper, Robert S., Zhou, Baohua, Janga, Sarath Chandra, Yang, Kai, Kaplan, Mark H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523001/
https://ncbi.nlm.nih.gov/pubmed/32985505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18648-6
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