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LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling

Mechano-sensory hair cells within the inner ear cochlea are essential for the detection of sound. In mammals, cochlear hair cells are only produced during development and their loss, due to disease or trauma, is a leading cause of deafness. In the immature cochlea, prior to the onset of hearing, hai...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Li, Xiao-Jun, Doetzlhofer, Angelika
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486708/
https://ncbi.nlm.nih.gov/pubmed/32826333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000417117
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