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LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling

Mechano-sensory hair cells within the inner ear cochlea are essential for the detection of sound. In mammals, cochlear hair cells are only produced during development and their loss, due to disease or trauma, is a leading cause of deafness. In the immature cochlea, prior to the onset of hearing, hai...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Proc Natl Acad Sci U S A
Κύριοι συγγραφείς: Li, Xiao-Jun, Doetzlhofer, Angelika
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486708/
https://ncbi.nlm.nih.gov/pubmed/32826333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000417117
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