Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis

In humans and in mice the formation of nephrons during embryonic development reaches completion near the end of gestation, after which no new nephrons are formed. The final nephron complement can vary 10-fold, with reduced nephron number predisposing individuals to hypertension, renal, and cardiovas...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yermalovich, Alena V., Osborne, Jihan K., Sousa, Patricia, Han, Areum, Kinney, Melissa A., Chen, Michael J., Robinton, Daisy A., Montie, Helen, Pearson, Dan S., Wilson, Sean B., Combes, Alexander N., Little, Melissa H., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329821/
https://ncbi.nlm.nih.gov/pubmed/30635573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08127-4
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