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Hamartin regulates cessation of mouse nephrogenesis independently of Mtor

Nephrogenesis concludes by the 36th week of gestation in humans and by the third day of postnatal life in mice. Extending the nephrogenic period may reduce the onset of adult renal and cardiovascular disease associated with low nephron numbers. We conditionally deleted either Mtor or Tsc1 (coding fo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Volovelsky, Oded, Nguyen, Thi, Jarmas, Alison E., Combes, Alexander N., Wilson, Sean B., Little, Melissa H., Witte, David P., Brunskill, Eric W., Kopan, Raphael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003359/
https://ncbi.nlm.nih.gov/pubmed/29784808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712955115
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