Mechanisms Mediating High-Molecular-Weight Hyaluronan-Induced Antihyperalgesia

We evaluated the mechanism by which high-molecular-weight hyaluronan (HMWH) attenuates nociceptor sensitization, in the setting of inflammation. HMWH attenuated mechanical hyperalgesia induced by the inflammatory mediator prostaglandin E2 (PGE(2)) in male and female rats. Intrathecal administration...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Bonet, Ivan J.M., Araldi, Dionéia, Khomula, Eugen V., Bogen, Oliver, Green, Paul G., Levine, Jon D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486649/
https://ncbi.nlm.nih.gov/pubmed/32665406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0166-20.2020
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