CD44 Signaling Mediates High Molecular Weight Hyaluronan-Induced Antihyperalgesia

We studied, in male Sprague Dawley rats, the role of the cognate hyaluronan receptor, CD44 signaling in the antihyperalgesia induced by high molecular weight hyaluronan (HMWH). Low molecular weight hyaluronan (LMWH) acts at both peptidergic and nonpeptidergic nociceptors to induce mechanical hyperal...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Ferrari, Luiz F., Khomula, Eugen V., Araldi, Dioneia, Levine, Jon D.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761612/
https://ncbi.nlm.nih.gov/pubmed/29175954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2695-17.2017
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