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CD44 Signaling Mediates High Molecular Weight Hyaluronan-Induced Antihyperalgesia

We studied, in male Sprague Dawley rats, the role of the cognate hyaluronan receptor, CD44 signaling in the antihyperalgesia induced by high molecular weight hyaluronan (HMWH). Low molecular weight hyaluronan (LMWH) acts at both peptidergic and nonpeptidergic nociceptors to induce mechanical hyperal...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Ferrari, Luiz F., Khomula, Eugen V., Araldi, Dioneia, Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761612/
https://ncbi.nlm.nih.gov/pubmed/29175954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2695-17.2017
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