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Sexual Dimorphism in a Reciprocal Interaction of Ryanodine and IP(3) Receptors in the Induction of Hyperalgesic Priming
Hyperalgesic priming, a model of pain chronification in the rat, is mediated by ryanodine receptor-dependent calcium release. Although ryanodine induces priming in both sexes, females are 5 orders of magnitude more sensitive, by an estrogen receptor α (EsRα)-dependent mechanism. An inositol 1,4,5-tr...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338754/ https://ncbi.nlm.nih.gov/pubmed/28115480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2911-16.2017 |
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