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Function and aggregation in structural eye lens crystallins

Crystallins are transparent, refractive proteins that contribute to the focusing power of the vertebrate eye lens. These proteins are extremely soluble, resisting aggregation for decades, even under crowded conditions. Crystallins have evolved to avoid strong inter-protein interactions and have unus...

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Bibliographic Details
Published in:Acc Chem Res
Main Authors: Roskamp, Kyle W., Paulson, Carolyn N., Brubaker, William D., Martin, Rachel W.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486140/
https://ncbi.nlm.nih.gov/pubmed/32271004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00014
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