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Targeting prenylation inhibition through the mevalonate pathway
Protein prenylation is a critical mediator in several diseases including cancer and acquired immunodeficiency syndrome (AIDS). Therapeutic intervention has focused primarily on directly targeting the prenyltransferase enzymes, FTase and GGTase I and II. To date, several drugs have advanced to clinic...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | RSC Med Chem |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Royal Society of Chemistry
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7485146/ https://ncbi.nlm.nih.gov/pubmed/33479604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00442d |
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