Regulation of VEGF by mevalonate pathway inhibition in breast cancer

Aminobisphosphonates are used for the treatment of benign and malignant bone disorders. As inhibitors of the mevalonate pathway they exert direct anti-tumor effects in vitro and in preclinical models of bone metastases. Bisphosphonates are thought to have an anti-angiogenic activity as decreased lev...

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Publicat a:J Bone Oncol
Autors principals: Rachner, Tilman D., Göbel, Andy, Junker, Maria, Hötzel, Josefa, Benad-Mehner, Peggy, Hadji, Peyman, Hofbauer, Lorenz C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4723384/
https://ncbi.nlm.nih.gov/pubmed/26909280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2013.05.003
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