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Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer

BACKGROUND: Ovarian cancer remains the most fatal gynecological malignancy. Current therapeutic options are limited due to late diagnosis in the majority of the cases, metastatic spread to the peritoneal cavity and the onset of chemo-resistance. Thus, novel therapeutic approaches are required. Stati...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Göbel, Andy, Zinna, Valentina M., Dell’Endice, Stefania, Jaschke, Nikolai, Kuhlmann, Jan Dominik, Wimberger, Pauline, Rachner, Tilman D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388525/
https://ncbi.nlm.nih.gov/pubmed/32727400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07164-x
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