Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer

BACKGROUND: Ovarian cancer remains the most fatal gynecological malignancy. Current therapeutic options are limited due to late diagnosis in the majority of the cases, metastatic spread to the peritoneal cavity and the onset of chemo-resistance. Thus, novel therapeutic approaches are required. Stati...

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Pubblicato in:BMC Cancer
Autori principali: Göbel, Andy, Zinna, Valentina M., Dell’Endice, Stefania, Jaschke, Nikolai, Kuhlmann, Jan Dominik, Wimberger, Pauline, Rachner, Tilman D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7388525/
https://ncbi.nlm.nih.gov/pubmed/32727400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07164-x
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