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Targeting the Mevalonate Pathway in Cancer
The mevalonate synthesis inhibitors, statins, are mainstay therapeutics for cholesterol management and cardiovascular health. Thirty years of research has uncovered supportive roles for the mevalonate pathway in numerous cellular processes that support oncogenesis, most recently macropinocytosis. Ce...
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| Publicado no: | Trends Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8137523/ https://ncbi.nlm.nih.gov/pubmed/33358111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.11.008 |
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