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Update on mutations in the HIF: EPO pathway and their role in erythrocytosis
Identification of the underlying defects in congenital erythrocytosis has provided mechanistic insights into the regulation of erythropoiesis and oxygen homeostasis. The Hypoxia Inducible Factor (HIF) pathway plays a key role in this regard. In this pathway, an enzyme, Prolyl Hydroxylase Domain 2 (P...
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| Pubblicato in: | Blood Rev |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484688/ https://ncbi.nlm.nih.gov/pubmed/31350093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2019.100590 |
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