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Growth Optimized Aminoacyl-tRNA Synthetase Levels Prevent Maximal tRNA Charging
Aminoacyl-tRNA synthetases (aaRSs) serve a dual role in charging tRNAs. Their enzymatic activities both provide protein synthesis flux and reduce uncharged tRNA levels. Although uncharged tRNAs can negatively impact bacterial growth, substantial concentrations of tRNAs remain deacylated even under n...
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| 出版年: | Cell Syst |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484455/ https://ncbi.nlm.nih.gov/pubmed/32726597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.07.005 |
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