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Growth Optimized Aminoacyl-tRNA Synthetase Levels Prevent Maximal tRNA Charging
Aminoacyl-tRNA synthetases (aaRSs) serve a dual role in charging tRNAs. Their enzymatic activities both provide protein synthesis flux and reduce uncharged tRNA levels. Although uncharged tRNAs can negatively impact bacterial growth, substantial concentrations of tRNAs remain deacylated even under n...
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| Publicado no: | Cell Syst |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484455/ https://ncbi.nlm.nih.gov/pubmed/32726597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.07.005 |
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